Porin was used as a loading control. Low-dose aspirin is known to profoundly inhibit platelet COX-1 activity 2225but low-dose, aspirin-insensitive TXA 2 production has been reported in patients with unstable coronary syndromes 34 Comparative Toxicogenomics Database More The respective IC 50 s are indicated on each plot. Bulk Orders Add to Cart.
The asterisk indicates a non-specific band that crossreacts with the COX20 antibody.
Prostaglandin G/H synthase 2
Increased decrease of protein stability; when associated with A A single clone containing the most predominant nucleotide sequence was ligated to a partial COX-2 cDNA to generate full-length cDNA for protein expression in insect cells. Therefore, COX-2 expression may be specifically related to the megakaryocytopoiesis, whereas the myeloid differentiation appears to up-regulate COX-1 instead 89. Co-transfection of the TALEN pair into HEKT cells was expected to generate double strand DNA breaks in the first exon of the COX20 gene and, since the non-homologous end joining repair system often yields small deletions or insertions 35an out-of frame mutation and a nonsense transcript that leads to the absence of COX20 protein. The product is shipped at ambient temperature. Integrated resource of protein families, domains and functional sites More