There have been only a few reports of men with Down's syndrome fathering children. Effect of maternal smoking and coffee consumption on the risk of having a recognized Down syndrome pregnancy. Also determination of metabolites in blood or urine is possible to detect these diseases. The influence of parental age on Down syndrome. Nothing is known which could have stopped the parent giving an extra chromosome. A very few children with translocation have partial trisomy 21 - where only a part of chromosome 21 is present in 3 copies. Distribution pattern of seven risk factors in control and Down syndrome families.
A total of seven different possible risk factors were assessed in control and DS families as well as in control and 25 SA families.
The Genetics of Down's Syndrome
Mechanisms of Ageing and Development. Why does regular trisomy 21 happen? Reproductive performance of mother The major issues in women's reproductive health are fertility regulation, abortion, maternal mortality, sexually transmitted diseases, and infertility. The dementia which occurs in Down syndrome is due to an excess of amyloid beta peptide produced in the brain and is similar to Alzheimer's disease. Royal Society of Medicine Press.